The first mention of Głębokie in historical sources comes from 1414 and this date shall be considered as time of the founding of the first settlement. In 1514 Głębokie was included in the documents of the Grand Duchy of Lithuania. Jews first settled in Głębokie during the 17th century, and by the end of the 19th century represented about 70% of the town's 5,600 residents.

According to the Polish census of 1921, some 2,844 Jews lived in Głębokie, accounting for 63% of its population. Just before the Soviet invasion of Poland in World War II, Głębokie had a population of 9,700.

Hlybokaye was occupied by the German on July 2nd, 1941. Shortly thereafter the Germans enacted a number of anti-Jewish laws, including the mandating of the seizure of personal property, and established a Judenrat. The Jews of Hlybokaye were relocated into a ghetto in October 1941. Mass killings of Jews began around this time and continued during the German occupation. During this time Jews from neighboring communities were resettled in the Hlybokaye ghetto, such that the population grew to around 4,000 by the summer of 1943. The Germans began to liquidate the ghetto in August 1943.

This Yizkor Book serves as a memorial to all the victims of the Shoah from Glubokie and the neighboring communities.